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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATM
All Species:
14.55
Human Site:
Y423
Identified Species:
35.56
UniProt:
Q13315
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13315
NP_000042.3
3056
350687
Y423
A
T
Q
L
I
S
K
Y
P
A
S
L
P
N
C
Chimpanzee
Pan troglodytes
XP_001139487
3056
350692
Y423
A
T
Q
L
I
S
K
Y
P
A
S
L
P
N
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62388
3066
349469
Y422
T
T
R
L
I
S
K
Y
P
S
S
L
P
N
C
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001155872
3050
347768
Y421
T
A
R
L
L
S
K
Y
P
M
S
F
P
N
C
Frog
Xenopus laevis
Q9DE14
2654
301441
H164
F
E
D
L
I
Y
I
H
E
Q
N
M
E
K
S
Zebra Danio
Brachydanio rerio
XP_002667249
1913
215524
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q5EAK6
2767
317973
F277
D
D
T
R
N
L
F
F
Q
C
V
S
K
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107666
3120
349933
Y433
L
A
A
L
V
T
K
Y
P
K
D
L
P
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M3G7
3856
435096
P1017
Q
S
L
L
E
N
S
P
G
D
F
P
D
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RZT9
2939
328678
R398
L
T
M
V
F
G
L
R
P
Y
H
L
A
G
E
Conservation
Percent
Protein Identity:
100
99.4
N.A.
N.A.
N.A.
83.8
N.A.
N.A.
N.A.
69.5
20.5
35.1
N.A.
22.1
N.A.
N.A.
36.2
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
91.3
N.A.
N.A.
N.A.
82.8
39.9
46.3
N.A.
42.8
N.A.
N.A.
56.7
P-Site Identity:
100
100
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
60
13.3
0
N.A.
0
N.A.
N.A.
40
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
73.3
33.3
0
N.A.
13.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.9
N.A.
20.8
Protein Similarity:
N.A.
N.A.
N.A.
42.5
N.A.
40.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
10
0
0
0
0
0
0
20
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
40
% C
% Asp:
10
10
10
0
0
0
0
0
0
10
10
0
10
10
0
% D
% Glu:
0
10
0
0
10
0
0
0
10
0
0
0
10
10
20
% E
% Phe:
10
0
0
0
10
0
10
10
0
0
10
10
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
40
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
50
0
0
10
0
0
10
10
0
% K
% Leu:
20
0
10
70
10
10
10
0
0
0
0
50
0
0
20
% L
% Met:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
10
0
0
40
0
% N
% Pro:
0
0
0
0
0
0
0
10
60
0
0
10
50
0
0
% P
% Gln:
10
0
20
0
0
0
0
0
10
10
0
0
0
0
0
% Q
% Arg:
0
0
20
10
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
40
10
0
0
10
40
10
0
10
10
% S
% Thr:
20
40
10
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
50
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _